AM-2233

$160.00

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  • $160.00
  • $160.00
  • $160.00
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AM-2233

AM2233 is a full agonist of the central cannabinoid (CB1) receptor (Ki = 2.8 nM). Most of the affinity towards the CB1 receptor resides within the (R)-enantiomer of AM2233, which exhibits a Ki value of 0.2 nM and has ~8-fold higher affinity for CB1 compared to WIN 55,212-2 (Ki = 1.6 nM).

AM2233 was developed for use as a selective radioligand for mapping the distribution of the CB1 receptor in the brain. Recently, however, AM2233 has received attention as a cannabimimetic acquired for recreational use as a “legal high” replacement for restricted substances. This compound is intended for forensic and research applications.

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